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ABP02-10

ABP02-10

Anti-Proteinase 3 IgG

Goat anti-Human antibody (Protein G purified)
US $218.00
Vial Size
Qty.
Purification: Purified using protein G affinity chromatography
Immunogen: Native proteinase 3 antigen (Myeloblastin, p29, AGP7) purified from human neutrophils
Applications: Immunocytochemistry, Western blot, sandwich ELISA
Autoantibodies present in vasculitic diseases and Wegener’s granulomatosis
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Davies DJ. et al. (1982) Segmental necrotising glomerulonephritis with antineutrophil antibody: possible arbovirus aetiology?
Br Med J (Clin Res Ed). 285, 606
Lüdemann J et al. (1990) Anti-neutrophil cytoplasm antibodies in Wegener's granulomatosis recognize an elastinolytic enzyme.
J Exp Med. 171, 357-62
Gupta SK et al. (1990) Identity of Wegener's autoantigen (p29) with proteinase 3 and myeloblastin. Blood. 76, 2162
Jenne DE et al. (1990) Wegener's autoantigen decoded. Nature. 346, 520
Gaskin G et al. (1995) Use of proteinase 3 purified by reverse phase HPLC to detect autoantibodies in systemic vasculitis.
J Immunol Methods. 180, 25-33
Stummann L et al. (1997) A simple high yield procedure for purification of human proteinase 3, the main molecular target of cANCA. J Immunol Methods. 206, 35-42
Heegaard NH et al. (1997) Purification of Wegener's granulomatosis autoantigen, proteinase 3, from neutrophils by Triton X-114 extraction of azurophilic granules. Anal Biochem 253, 259-62
Kallenberg CG et al. (1990) Solid phase assays for ANCA. Neth J Med. 36, 132-6
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AROTEC Diagnostics
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