High purity diagnostic reagents with exceptional lot-to-lot consistency

AROTEC autoantigens have a minimum specification of >90% purity. This high level of purity is achieved through advanced chromatographic techniques and careful “polishing” of the final products.

Our purification strategies are designed to minimize potential contaminants, ensuring low background signals for reliable assay performance.

Our highly active autoantigens can be used at very low concentrations in ELISA, down to 10-100ng/well, offering a cost effective source for your diagnostic needs.

Both linear and conformation-dependent autoantibody epitopes are detected with high sensitivity.

Utilising native sourced material where possible ensures your reagents have the correct post-translational processing along with the correct tertiary and quaternary structure.

In some assays this is essential for the detection of conformation-dependent autoantibodies. Our human neutrophil purified autoantigens offer the most authentic autoantibody targets.

Animal sourced autoantigens also possess structure authenticity, and high degrees of homology to the human sequence.

Using active immunoabsorption procedures, result in our highly pure products being highly specific, by removing potentially interfering components where necessary.

Strict quality control measures ensures our products are free of other proteins which could lead to false positive results.

Consistency of lots is of utmost importance. 
Our strictly qualified native raw materials provide a reliable and reproducible source material.

Validated production processes are subjected to continuous in-process quality control resulting in the consistent high-end product produced at AROTEC.

Each new lot is rigorously tested to ensure they conform to our internal gold-standard references.